Small Volume Parenterals in the 2 to 5 mL range most commonly utilize a luer lock or luer slip fit (vented luer) top geometry. Syringes can be connected directly to the ampoules without a needle, creating an inherently safer delivery method.
A syringe with a needle can also be used, since a larger percentage of the smaller ampoules are used to provide diluent to reconstitute lyophilized drugs.